Methadone

• Drug Name: Methadone
• Generic Name: Methadone
• Brand Names: Methadose, Dolophine
• Drug Class: Opioid analgesic

About the Drug

Methadone is a long-acting opioid analgesic used for pain relief and as part of drug addiction detoxification and maintenance programs. It works by changing how the brain and nervous system respond to pain and reducing withdrawal symptoms in people addicted to heroin or other narcotic drugs.

Uses of the Drug

Methadone is primarily used for:

• Relief of moderate to severe pain
• Detoxification and maintenance treatment of opioid addiction
• Management of chronic pain in patients who require continuous, around-the-clock opioid analgesia

Warnings

• Methadone can cause addiction, overdose, or death if misused.
• It can cause severe drowsiness or breathing problems, especially when combined with alcohol or other drugs.
• Do not use methadone if you are pregnant, as it can cause withdrawal symptoms in a newborn.
• Methadone is not recommended for use in children younger than 18 years of age.
• Avoid using methadone if you have severe asthma, breathing problems, or a bowel obstruction.

Before Taking the Medicine

• Inform your doctor if you have a history of breathing problems, liver disease, kidney disease, a history of drug or alcohol addiction, heart disease, or seizures.
• Do not use methadone if you are allergic to it or other opioids.
• Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

How Should the Medicine [Methadone] Be Taken?

• Take methadone exactly as prescribed by your doctor.
• Follow all directions on your prescription label.
• Do not take in larger or smaller amounts or for longer than recommended.
• Swallow the tablet whole with a glass of water.
• Measure liquid medicine with the provided measuring device.

Dosing Information

• The usual dose for pain relief is 2.5 mg to 10 mg taken every 8 to 12 hours as needed.
• The dose for detoxification and maintenance of opioid addiction varies and is typically administered under the supervision of a healthcare provider.
• Dosage may be adjusted by your doctor based on your response to the medication.
• Do not exceed the prescribed dose to avoid serious side effects, including respiratory depression.

What Happens If a Dose Is Missed?

• Take the missed dose as soon as you remember.
• Skip the missed dose if it is almost time for your next scheduled dose.
• Do not take extra medicine to make up for the missed dose.

What to Avoid While Taking the Medicine [Methadone]

• Avoid drinking alcohol while taking methadone, as it can increase the risk of severe side effects.
• Avoid driving or operating machinery until you know how methadone will affect you.

Medicine Side Effects

• Common Side Effects: Drowsiness, dizziness, nausea, vomiting, constipation, sweating, lightheadedness, dry mouth.
• Serious Side Effects: Respiratory depression, severe allergic reactions, confusion, hallucinations, severe drowsiness, difficulty urinating, severe constipation, seizures.

Medicine Interactions

• Methadone can interact with several other drugs, including antidepressants, sedatives, sleeping pills, muscle relaxers, and medications for anxiety or seizures.
• Inform your doctor about all your current medications and any new medications you start or stop using.

What Other Drugs Will Affect the Medicine?

• Inform your doctor if you use other medications that cause drowsiness, such as sleep aids, muscle relaxers, or medicines for anxiety, depression, or seizures.
• Avoid using alcohol or illegal drugs while taking methadone.

Generic Availability

• Generic versions of methadone are available.

Drug Prescribing Information

• Follow the prescribing information provided by your healthcare provider or the pharmacy.

Other Brands

• Methadose, Dolophine

Other Formulations

• Methadone is available in various strengths and formulations, including tablets, liquid, and injectable forms.

Medical Disclaimer

• This information is provided for educational purposes only and is not intended for medical advice. Always consult your doctor or pharmacist before using any medication.

10 Popular FAQ About the Drug

1. What is methadone used for?
   • It is used to relieve moderate to severe pain and for detoxification and maintenance treatment of opioid addiction.
2. Can I take methadone if I am pregnant?
   • Methadone is not recommended during pregnancy due to potential harm to the unborn baby.
3. How should I store methadone?
   • Store at room temperature away from moisture and heat.
4. Can I drink alcohol while taking methadone?
   • No, drinking alcohol can increase the risk of severe side effects.
5. What should I do if I miss a dose?
   • Take the missed dose as soon as you remember, but skip it if it’s almost time for your next dose.
6. Can I drive after taking methadone?
   • Avoid driving or operating heavy machinery until you know how methadone affects you.
7. Are there any serious side effects?
   • Yes, serious side effects include severe allergic reactions, respiratory depression, and seizures.
8. Can methadone cause addiction?
   • Yes, methadone can be addictive, and misuse can lead to dependence and overdose.
9. What other medications can interact with methadone?
   • Medications that cause drowsiness, other opioids, muscle relaxers, and certain antidepressants.
10. Is there a generic version of methadone?
    • Yes, generic versions are available.

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