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Ketamine is a dissociative anesthetic widely used in both human and veterinary medicine. It has garnered attention in recent years for its rapid-acting antidepressant properties and its potential use in treating various mental health conditions.

Chemical Overview:

• Chemical Name: Ketamine
• Molecular Formula: C13H16ClNO
• CAS Number: 6740-88-1
• Appearance: White crystalline powder
• Purity: 98%

Uses and Effects:

Medical Use:

• Anesthesia: Ketamine is used as an anesthetic in surgeries and diagnostic procedures due to its potent anesthetic and analgesic properties. It is often chosen for its ability to induce a trance-like state while providing pain relief.
• Pain Management: In lower doses, ketamine can be used to manage acute and chronic pain, including in patients who do not respond well to conventional pain medications.

Psychiatric Use:

• Antidepressant Effects: Ketamine has been found to provide rapid relief from depressive symptoms, often within hours, compared to traditional antidepressants. It is used off-label for treatment-resistant depression and bipolar disorder.
• Suicidal Ideation: Studies suggest ketamine can significantly reduce suicidal thoughts in individuals with severe depression, offering a potential lifeline for those in crisis.

Recreational Use:

• Dissociative Effects: At recreational doses, ketamine induces dissociation from the environment and oneself, often described as an “out-of-body” experience or “K-hole.” This can include altered perceptions of time and space.
• Euphoria and Hallucinations: Users report feelings of euphoria and visual or auditory hallucinations. It is often sought after for its unique psychoactive effects.

Dosage Information:

• Medical Dosage: In a clinical setting, ketamine is administered intravenously or intramuscularly in precise doses tailored to the patient’s needs.
• Recreational Dosage: Recreational doses typically range from 50 mg to 200 mg, depending on the desired effects. Users should exercise caution as higher doses can lead to unpleasant experiences and impaired motor function.

Potential Side Effects:

• Dissociation and Confusion: Users may experience disorientation, confusion, and impaired coordination. These effects can interfere with daily activities and judgment.
• Nausea and Vomiting: Common side effects include nausea and vomiting, especially with higher doses.
• Increased Blood Pressure: Ketamine can cause a temporary increase in blood pressure and heart rate, which could be risky for individuals with cardiovascular conditions.
• Bladder Issues: Long-term use has been associated with urinary tract and bladder problems, including inflammation and pain.
• Hallucinations and Delusions: High doses or repeated use can lead to persistent hallucinations or delusions, requiring medical intervention.

Legality:

Ketamine’s legal status varies by country and region. It is generally classified as a controlled substance due to its potential for abuse. Medical use is regulated, while recreational use is often prohibited. Buyers should verify local laws to ensure compliance.

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Ketamine is a hallucinogenic dissociative and anaesthetic that is used in both humans and animals for medical purposes. It was synthesised in 1962, and used in anaesthesia as an alternative to phencyclidine (PCP) which caused powerful, long lasting hallucinations and psychotic symptoms. Today it is often used as an anaesthetic in children or those undergoing minor surgery. It is most frequently used now in veterinary medicine. It is on the World Health Organisation’s list of essential medicines.

In low doses, users report a similar feeling to being drunk. Higher doses cause a much more dissociative or psychedelic effect. When used as a medicine, ketamine is a clear liquid. “Street” ketamine is usually a white powder; with a grainy appearance like salt, or flaky like tiny glass shards.

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