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Diphenidine, also known as 1-(1,2-Diphenylethyl)piperidine, is a dissociative research chemical that acts as an NMDA receptor antagonist, similar in effects to ketamine and PCP. It was first identified in 2013 and has since been studied in the context of neurological research, particularly for its dissociative and analgesic properties.

Chemical Overview:

  • Chemical Name: 1-(1,2-Diphenylethyl)piperidine
  • Molecular Formula: C19H23N
  • CAS Number: 22348-32-9
  • Appearance: White crystalline powder
  • Purity: 98.99%

Diphenidine is often available in its pure powdered form, ensuring consistency in research studies that explore its dissociative effects and potential use in understanding NMDA receptor antagonism.

Uses and Effects:

Diphenidine has been researched for a variety of effects:

  • Dissociation: Provides an out-of-body or detached mental state, making it a prime subject for dissociative studies.
  • Analgesic Properties: Similar to other NMDA antagonists, Diphenidine can provide relief from pain by blocking certain neural pathways, making it of interest in pain management research.
  • Euphoria: Some users report feelings of euphoria, although this is secondary to the dissociative effects.
  • Cognitive Suppression: It has been shown to impair cognitive function temporarily, including memory and problem-solving abilities.

Potential Side Effects:

As with any research chemical, Diphenidine has potential side effects that should be considered in any controlled setting:

  • Motor Control Impairment: Similar to ketamine, Diphenidine can lead to poor coordination and difficulty with movement.
  • Confusion and Disorientation: High doses may lead to intense confusion and a sense of disconnection from reality.
  • Nausea: Gastrointestinal discomfort or nausea may occur, especially in higher doses.
  • Increased Heart Rate and Blood Pressure: Stimulant-like effects on the cardiovascular system, such as elevated heart rate and blood pressure.
  • Anxiety or Paranoia: At higher doses, dissociative chemicals may induce anxiety, paranoia, or delusional thinking.
  • Risk of Psychosis: As with other dissociatives, repeated high-dose use can lead to psychotic symptoms or prolonged dissociation.

Dosage Information:

Diphenidine has been researched in the following dose ranges:

  • Low Dose: 30-50 mg
  • Common Dose: 50-80 mg
  • High Dose: 100-150 mg

The effects of Diphenidine typically last 4-6 hours, with the peak occurring 1-2 hours after administration. Its duration and effects can vary based on dosage and individual response.

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